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Orlistat causes steatorrhea (fatty stools), urgency, and fecal incontinence

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Lets say a patient starts at 230 pounds

Although the exact mechanism of action remains an area of interest, there are hypotheses as to why incretin analogs and GLP-1RA are effective in FPLD

DOSING USED IN PHASE 3 STUDIES In the most recent studies from the TRIUMPH programme (Phase 3) , retatrutide was administered as follows: Route: Subcutaneous Frequency: Once weekly Study duration: Approximately 68 weeks Recommended Dosage (Clinical Research Escalation Model) Retatrutide is administered once weekly using a gradual dose escalation to improve tolerability